HSIL. CIN 2 or CIN 3 has been reported in at least 70 percent of women with cytology results of high-grade squamous intraepithelial lesions (HSIL), and 1 to 2 percent have invasive cancer. Given the level of risk, colposcopy and biopsy of visible lesions are recommended.
Can HSIL be benign?
HSIL is a squamous cell abnormality associated with human papillomavirus (HPV). Though not all HSILs will progress to cancer, HSIL is considered a precancerous lesion and is usually treated aggressively.
Should I worry about low grade squamous intraepithelial lesion?
LSIL often resolves on its own or can be effectively treated to help prevent development of cervical cancer. Although LSIL is not cancer, regular (and follow-up, if needed) Pap screenings are important in order to identify and treat abnormal cells before they become cancerous.
What is the progression rate of HSIL?
High-grade anal intraepithelial neoplasia (HSIL) is believed to be the direct precursor to anal cancer. The rate of progression of HSIL to invasive carcinoma is 1.3% and 3.2% at 5 years in two recent reviews [1, 2].
What is the best treatment for HSIL?
HSIL (CIN2/3) Colposcopy). Ablative methods such as CO2 laser ablation are effective but infrequently used in modern practice. Excisional methods such a large loop excision of the TZ (LLETZ), loop electrosurgical excision procedure (LEEP) or cold-knife cone biopsy are preferred.
How serious are precancerous cells in uterus?
Precancerous cells may or may not turn into cancer. Because the cells are abnormal, it's important to have them monitored or, in some cases, removed to help reduce your future risk of cancer.